Epi Info is statistical software for epidemiology developed by Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia (US).

Epi Info has been in existence for over 20 years and is currently available for Microsoft Windows, Android and iOS, along with a web and cloud version.

The first version, Epi Info 1, was originally developed by Jeff Dean while he was in high school.

[5] MS-DOS continued to be the only supported operating system until the release of Epi Info 2000, which was written in Microsoft's Visual Basic and became the first Windows-compatible version.

After Microsoft shut down Codeplex in December 2017, the repository of Epi Info migrated to GitHub.

Epi Info uses three distinct modules to accomplish these tasks: Form Designer, Enter, and Analysis.

Check code allows for certain events to occur depending on what action a data entry person has taken.

Many advanced statistical routines are provided, such as t-tests, ANOVA, nonparametric statistics, cross tabulations and stratification with estimates of odds ratios, risk ratios, and risk differences, logistic regression (conditional and unconditional), survival analysis (Kaplan Meier and Cox proportional hazard), and analysis of complex survey data.

In Epi Info 7, the Visual Dashboard assumes some of the basic functions of the report module.

It replaces the NutStat and EpiNut modules found in prior versions of Epi Info.

[8] Examples of papers that used Epi Info for data entry include a study on nutrition[9] and an epidemiological survey about echinococcosis.