E. microphyllum grows epiphytically at low altitudes in the tropical rain forests of northern Brazil, Colombia, Ecuador (including a site in Napo at 180 m[1]), French Guiana, Guyana, Peru, Suriname, and Venezuela.

[2] The small sympodial plant bears rather widely separated (3–5 cm) short, erect stems covered with imbricating sheathes, most of which bear the thick, narrow, alternate leaves.

The petals are linear to narrowly elliptic, and bend backward to a lesser degree than the dorsal sepal.

The lateral margins of the pointed lip partially encircle the apex of the column.

[3] According to the Vienna code, the proper names for these subdivisions of the genus Epidendrum are E. sect.