Epigallocatechin gallate

EGCG – the most abundant catechin in tea – is a polyphenol under basic research for its potential to affect human health and disease.

][3] Trace amounts are found in apple skin, plums, onions, hazelnuts, pecans, and carob powder (at 109 mg per 100 g).

[2] When taken orally, EGCG has poor absorption even at daily intake equivalent to 8–16 cups of green tea, an amount causing adverse effects such as nausea or heartburn.

[7][8][9][10] A 2011 analysis by the European Food Safety Authority found that a cause and effect relationship could not be shown for a link between tea catechins and the maintenance of normal blood LDL-cholesterol concentration.

[11] A 2016 review found that high daily doses (107 to 856 mg/day) taken by human subjects over four to 14 weeks produced a small reduction of LDL cholesterol.

Structural formula of epigallocatechin gallate
Space-filling model of the epigallocatechin gallate molecule