First published in 2008 by BioMed Central, its overall aim is to understand the regulation of gene and chromosomal elements during the processes of cell division, cell differentiation, and any alterations in the environment.

[2] According to Journal Citation Reports, it received an impact factor of 4.237[3] in 2019.

[5] Current submission guidelines are as follows: Submitters must ensure that Epigenetics & Chromatin is the most suitable journal for the proposed article in addition to understanding of the costs, funding options, and copyright agreement associated with submission.

[7] The manuscript must follow all formatting rules which authors must read, understand and accept.

Authors should also be familiar with the process of manuscript transfers to a different journal, as well as how to promote the publication.