The district is bordered on the north by Lamminpää, on the east by Lielahti, on the south by Epilä and on the west by Tohloppi and Ristimäki.
The Epilänharju district is home to the former Epilä Spa, which has now been abandoned and left to decay, as well as Abloy Oy's former factory.
The Epilä House, which belonged to the village of Tohloppi, was already mentioned in the land register of 1540, and was located on the site of the later Winter's paint factory.
Industry began to emerge in the area at the turn of the 20th century, when the Tampere–Pori railway was completed.
Along with other western connection areas, Epilänharju was transferred from the municipality of the northern Pirkkala to the city of Tampere at the beginning of 1937.