It was built about 1768, and consists of a three-bay, 2+1⁄2-story, central block with hipped roof, dormers, modillion cornice, and flanking one-story wings in the Georgian style.

Mary (Polly) Jefferson (1778–1804), married in 1797 her cousin, John Wayles Eppes (1772–1823) and spent much of her time at Eppington.

[4] The Eppeses own daughters studied natural and agricultural sciences, noting what times of year crops came in as well as when Eastern whip-poor-wills arrived and started singing.

The General Assembly, in 1819, gave Archibald Thweatt, owner of Eppington, compensation from any damages but allowed the Upper Appomattox Canal company to build a dam and locks around the falls.

[3] When the Upper Appomattox Canal Navigation System was complete, neighboring farmers could ship farm produce from the docks at Eppington.

A boat that could carry seven tons of coal, made a four-day round trip to Petersburg for two dollars and thirty eight cents.