Epworth Hall is a historic building in Gainesville, Florida, United States.

Now part of the First United Methodist Church, it was added to the U.S. National Register of Historic Places on July 25, 1973.

Beginning in the 1906 academic year the university's classes were held at Epworth Hall, while the buildings were being constructed on the new campus away from downtown.

In 1911 the University of Florida completed its transition to the new campus, and deeded Epworth Hall to the First United Methodist Church, which still owns the property.

This article about a property in Alachua County, Florida on the National Register of Historic Places is a stub.