[1] Founded in 1984[2] after the murder of Charlie Howard,[3] it is the oldest and largest lesbian, gay, bisexual and transgender (LGBTQ) organization in the state.

[5][6] On June 30, 2011, EqualityMaine and Gay & Lesbian Advocates & Defenders (GLAD) announced plans to place a voter initiative in support of same-sex marriage on the state's November 2012 ballot.

Ali Vander Zanden, the political director for EqualityMaine, stated "[Michaud] has been a stalwart supporter of equal rights for all Mainers.

On May 10, 2018, Maine became the third state to offer a non-binary option listed on driver's licenses after Oregon and California.

[15] EqualityMaine operates out of the Equality Community Center in Portland, Maine and maintains an active social media presence that broadcasts upcoming events related to LGBT causes.