[2] Due to a papal edict preventing women from appearing onstage in Rome, it premiered with castrati singing all the female roles.

Although the score was believed to have been lost, 30 arias and 2 duets were discovered in several archives, and the rest of the opera was reconstructed by Alessandro Ciccolini.

To atone for killing his children in wrath, Hercules must perform twelve labors, the ninth of which is to travel to Thermodon and capture the sword of the Amazon Queen Antiope.

Hercules, accompanied by the heroes Theseus, Telamon and Alceste, attacks the Amazons and captures Martesia, daughter of the queen.

In the end, the goddess Diana decrees the marriage of Hippolyte with Theseus, prince of Athens, and of Martesia with Alceste, king of Sparta.