[1] Many clubs were interested, and on 20 March 2007, the league was officially unveiled by the KNVB for three seasons, with the first scheduled for 2007–08 with six clubs: ADO Den Haag, AZ, sc Heerenveen, FC Twente, FC Utrecht, and Willem II.

[6][7] On 29 August 2007, the opening ceremony for the launch of the Eredivisie Vrouwen took place at the Arke Stadion in Enschede, with the presentation of the six participating teams, ahead of the league's inaugural match played by FC Twente and sc Heerenveen in front of 5.500 spectators.

Marieke van Ottele scored the first ever Eredivisie goal for FC Twente, 73 seconds into the match.

[8][9] At the end of the 2007–08 season, AZ were crowned the first Eredivisie champions and Karin Stevens the top scorer with 20 goals.

[10] AZ won the championship for a second consecutive year, and Sylvia Smit was the top scorer with 14 goals.

Sylvia Smit, for the second consecutive season, and Chantal de Ridder were top scorers with 11 goals each.

A statement from the KNVB announced that for the next season, matchdays would move from Thursdays to Fridays, relationship changes between clubs and their affiliated amateur clubs, guideline principles amongst other topics discussed and the financial conditions were to be discussed on a further meeting, as the KNVB was trying to keep the league with eight teams next season.

[24] The 2011–12 season was won by ADO Den Haag, the club's first league title, and Priscilla de Vos was the top scorer, with 16 goals.

[25] On 10 December 2010, the KBVB agreed to go ahead with the BeNe League,[26] and two days later the KNVB decided to stop investing in the Eredivisie Vrouwen for the next three years.

[27] On 13 February 2012, the KNVB announced it was also going ahead with the BeNe League,[28] and on 23 March 2012, it received approval from UEFA.

[30] On 2 April 2015, the KNVB confirmed the restart of the Eredivisie Vrouwen with the participation of the seven Dutch clubs that played in the final BeNe League season.

[31] Ajax and PSV made their debut in the re-formed Eredivisie , as both clubs established women's teams in 2012.

They joined ADO Den Haag, SC Heerenveen, Telstar, FC Twente, and PEC Zwolle, which all returned to the Eredivisie after the 2011–12 season.

[33][34] Ajax won the title for the first time, and Telstar's Katja Snoeijs was the top scorer with 21 goals.

[43] In January 2022, Dutch media reported that Fortuna Sittard and Telstar would compete in the Eredivisie the following season,[44] taking the league to 11 clubs.

From 2016 to 2020, the season was split in two parts, a regular season, where all clubs play a triple round-robin format, and a playoff, where the top four teams, based on points, form a champions group and the remaining teams form a placement group.

From 2007 to 2012, the yearly Golden Shoe (Dutch: Gouden Schoen) was awarded to the best player of the Eredivisie Vrouwen.

In February 2021, Pure Energie signed a contract with the KNVB for naming rights to the Vrouwen Eredivisie.