[2] He dressed in his first professional game in the team's 2018 season opener on June 16, 2018 against the Hamilton Tiger-Cats.
In total, he dressed in 14 regular season games in 2018 where he recorded five special teams tackles.
Mezzalira also played in both post-season games, including in the 106th Grey Cup where he had one special teams tackle in the victory over the Ottawa Redblacks.
He did not play in 2020 due to the cancellation of the 2020 CFL season and he became a free agent upon the expiration of his rookie contract on February 9, 2021.
[6] On July 31, 2022, it was announced that Mezzalira had signed a practice roster agreement with the Montreal Alouettes.