Gustafsson played in the youth ranks of Timrå IK before enrolling at Northern Michigan University in 2007.

[1] Gustafsson made his NHL debut on 26 February 2011, against the Ottawa Senators, subbing for Chris Pronger, who was out with a bruised right hand.

[3] In the 2014–15 season, Gustafsson immediately established himself amongst the blueline with Omsk, finishing second among defenceman with 22 points in 56 games.

Despite early interest in the off-season from the NHL, on 17 July 2015, Gustafsson left Omsk as a free agent to sign a one-year contract with Swiss club, Kloten Flyers of the NLA.

[6] In making his debut in the SHL in the 2018–19 season, Gustafsson as captain led Luleå HF from the blueline, playing top-pairing minutes in recording 6 goals and 27 points in 49 games.