On March 29, 2008, she started a solo music career,[1] working under the management and promotion of J.P Room.
She has been featured as the opening act in various of her Senpai's concerts (Natsumi Abe, Morning Musume, Berryz Kobo and Cute), starting in August 2008.
She has debuted under a major label Hachama with the single "Otome no Inori", released on March 18, 2009.
Mano, along with S/mileage and Morning Musume will star in the CS-Fuji TV-TWO dorama Half Esper which will begin broadcasting in January 2010.
She's sent to Japan as a spy for the Queen of the United Kingdom, and ends up passing an idol audition, so she has trouble with her espionage duties.
The theme song of the show is "Matsuge no Saki ni Kimi ga Iru" (from Mano's first album).
Kai-Ki: Tales of Terror from Tokyo, a Japanese horror film in which she starred and had its world premiere at Club Nokia.
In 2011, Mano's radio show, "Mano-Deli", was replaced by Morning Musume 9th generation member Riho Sayashi's "Riho-Deli" Also in 2011, it was announced that Mano would star in a short film called "Miyuki's Wind Bell".
On April 18, it was announced that Mano, Maimi Yajima, Airi Suzuki, and Chisato Okai would star in a new stage play, Theatre In The Round.
On December 6, her manager announced that she would appear in a new drama, Shark, in January 2014, starring Johnnies Jr.
[5] On July 1, 2010, Mano made her first promotional appearance outside Japan at Club Nokia in Los Angeles for her movie debut in Kai-Ki: Tales of Horror.