Neighbours primarily centers on the residents of Ramsay Street and other Erinsborough locations, most prominently those situated within the Lassiters complex.

[7] The Blackburn English Language Centre in Burwood East, Victoria, and Coburg High School have both been used for location and exterior shots.

[8] Kenneth Muir (Roger Boyce) was principal of the school when the series began and Erinsborough High was regularly seen until 1986, when Scott Robinson (Jason Donovan), Charlene Mitchell (Kylie Minogue), Mike Young (Guy Pearce) and Jane Harris (Annie Jones) graduated.

Neighbours' oldest surviving prop is the school's emblem and motto, which is stuck on the doors leading from the car park to the studios.

The spin-off was summarised as focusing on "bullying, mental illness, sexuality, cultural diversity, parental and peer pressure, and teacher-student relationships.

"[11] In May 2011, Erinsborough High came fourth out of four in a poll run by Inside Soap to find reader's favourite fictional school, which they would most like to attend.

Former principal Susan Kennedy has retired, while Ramsay street residents Nell Rebecchi, and JJ and Dex Varga-Murphy, are students at the school.

[citation needed] Eirini Rising is a retirement complex situated within the High School site, established in 2024 by Terese Willis (Rebekah Elmaloglou).

[16] Terese hires Karl Kennedy (Alan Fletcher) as resident doctor and wellness expert,[17] followed by his wife Susan (Jackie Woodburne) as Operations Manager.

[18] Later in 2024, Terese is forced to resign from the project after her alcoholism relapse places the residents in danger, leaving Susan and Karl in charge.

[22] Alan Fletcher, who plays Doctor Karl Kennedy, said it was confusing for visitors and couriers when the studio reception was used for filming hospital scenes.

[29] In early 2010, bulldozers moved into the Lassiters complex lot to the begin work on revamping the sets ahead of the show's 25th anniversary in March 2010.

[9] During The Erinsborough Tornado storyline in 2014, Lou Carpenter (Tom Oliver) was trapped in Harold's Store with Susan Kennedy (Jackie Woodburne), who had to perform an emergency tracheotomy on him when he began choking on some food.

Lastly, the Erinsborough News moved into the complex in 2010, with its set updated to include working interiors, which allowed camera crews to shoot indoors.

[7][55] A gas leak in the basement caused an explosion, which destroyed the pub and injured Stephen Gottlieb (Lochie Daddo).

[61] Celeste hires Kate Ramsay (Ashleigh Brewer) to replace her, while Natasha Williams (Valentina Novakovic) is employed as a barmaid and waitress.

She said "Although the Coffee House in Neighbours was arguably more important to the residents of Ramsay Street, Lou's gets included by dint of having the most rubbish name for a TV pub ever.

[66] In September 2014, a Soap World columnist praised the name change, saying "the rebranding of the pub with the iconic 'Waterhole' moniker has been a great move.

The constructed sandy area around the bar has been recreationally used for a volleyball tournament and a Longest Workout competition, involving a number of characters.

[68][69] The Flamingo Bar is destroyed in early 2022 when a pylon falls on it during a storm, killing Britney Barnes (Montana Cox).

[73] An accident in the tram in 2021 saw the end of a love triangle storyline and threatened Dipi Rebecchi (Sharon Johal) and Amy Greenwood's (Jacinta Stapleton) lives.

Lou offers mechanic Ben Atkins (Brett Cousins) a chance to go into partnership with him, but Philip Martin (Ian Rawlings) decides to buy a two percent share of the garage to stop the arguments.

[36] Stephanie Scully (Carla Bonner) takes over the business on behalf of Drew's widow, Libby Kennedy (Kym Valentine).

[78][79] He sells the business to Danni Ferguson's (Laura McIntosh) mother in 2013, and she employs Mark Brennan (Scott McGregor).

[80] His younger brother, Tyler (Travis Burns), comes to Erinsborough in 2015 to work at the garage and shortly after, Mark quits to re-join the police force.

It was opened by Portia Grant (Sue Ingleton), and later managed by Madge (Anne Charleston) and Harold Bishop (Ian Smith).

[84] The Handywoman (also Carpenter's Cars, Erinsborough Motors and Dial-A-Kyle) is an independent builders yard run by Amy Williams (Zoe Cramond).

[87] He later sells his stock to help pay his debts, but he keeps the land and briefly becomes a silent partner in Kyle Canning's (Chris Milligan) handyman business, which is named Dial-A-Kyle.

[93] A reporter for the Sunday Mail thought it was safer for the characters to stay in the suburb, commenting, "Whenever any Ramsay Street residents leave the cosy confines of Erinsborough, something bad always happens to them.

"[127] When Erinsborough was entered into a "Most Liveable Suburb" competition, a Coventry Telegraph reporter scoffed at the idea, saying "Sure, if you can stand the frequent adultery, family feuds, drug abuse, kidnapping, deaths, health scares, hit-and-runs, financial ruin and marital breakdowns, then the sunny climate at least is rather agreeable.