Ernesto Alberto Mascheroni Castiglioni (Italian pronunciation: [erˈnɛsto maskeˈroːni]; 21 November 1907 – 3 July 1984) was a footballer from Uruguay.

In 1934, he moved to Italy to play for Ambrosiana (now Inter Milan) until 1936.

During this period, he represented the Italy national football team twice winning the 1933–35 Central European International Cup.

By the time of his death in July 1984, at the age of 76, he was the last surviving member of Uruguay's 1930 World Cup winning team; though it would be another 26 years before the death of the last surviving participant of that World Cup.

This biographical article about a football defender from Uruguay is a stub.