During the day, he dedicated himself to his school studies, and, during his free time, he was taught how to play the piano by his father, who happened to be a musician.

[3] After he graduated from high school, Ramos Antonini enrolled at the University of Puerto Rico in Río Piedras (which is now a part of San Juan) to study law.

[4] In 1937, he gained fame as a lawyer when he defended the members of the Puerto Rican Nationalist Party who were accused of breaking the law after permits issued by the Mayor of Ponce for a peaceful march in Ponce were withdrawn by the colonial governor of Puerto Rico at the time, General Blanton Winship.

He appeared before the U.S. Congress and defended the Puerto Rican workers who were being abused by the American companies established on the island.

They later moved to today's Urbanización Floral Park in Hato Rey, a barrio of Río Piedras, which was still a town independent from San Juan.

The memory of Ramos Antonini has been honored by the government of Puerto Rico naming an avenue and public structures after him.

On December 18, 1997, the Government of Puerto Rico approved the Law Number 166 which proclaims every April 24 from then on to be known as "Ernesto Ramos Antonini Day".