SKG 210 had its origins in Erprobungsgruppe 210 (Test Wing 210), formed at Köln-Ostheim airfield under the command of Hptm.

The unit then moved east to prepare for the attack on Soviet Russia as part of 2nd Air Corps and originally based at Radzyn.

The Bf 110 provided support to the German Army, carrying out strike missions in the face of heavy AA and ground defences.

[1] SKG 210 flew over the Central part of the front supporting the German army's encirclement and overrunning of Russian land forces in the Białystok and Minsk areas in the early phase of the campaign, and flew in support of the advancing Army Group Centre to Moscow in 1941.

[2] With the coming of winter SKG 210 continued to operate in support of the army, covering their retreat.