A growing interest in religious and moral matters led her into non-fiction and journalism, sometimes in partnership with the writer J. D. Beresford.

[2] Educated first by governesses, then at an English boarding school and at a Belgian convent, she became a child-actress, taking the stage name Esmé Wynne in 1909.

She became a convert to Christian Science and vegetarianism and was estranged from the worldly life of the theatre, though she remained friendly with Coward, who was amused at her attempts to improve his moral character.

[6] In the years after her marriage, Wynne-Tyson wrote a series of novels: Security, 1927; Quicksand, 1927; Momus, 1928; Melody, 1929; and Incense and Sweet Cane, 1930.

[2] After the separation, she turned to non-fiction and journalism as well as fiction, often in collaboration with John Davys Beresford, who shared her interest in metaphysics and in a mutual gospel she later named "philosophy of compassion".

[3] Wynne-Tyson's non-fiction works include Prelude to Peace: The World-Brotherhood Educational Movement, 1936; The Unity of Being, 1949; This Is Life Eternal: The Case for Immortality, 1951; (under the pseudonym Peter de Morny) The Best Years of Their Lives, 1955; Mithras, the Fellow in the Cap, 1958; The Philosophy of Compassion: The Return of the Goddess, 1962; and (as editor) Porphyry's Abstinence from Animal Food, 1965.