The stadium has undergone several renovations, including in 1997; 2007; 2008; 2015, with the change of colors alluding to the country's flag (blue and white); and the most recent in 2020, with the installation of a new screen 100m² 4K LED and 54 new 1,500-watt metal halide luminaires with a capacity of 1,000 luxes, and an automated irrigation system.

Its creation was made possible by EDESSA (Estadios Deportivos de El Salvador) who in 1969 first proposed the idea of a new national stadium.

Construction began on 24 March 1971, with then-president of El Salvador General Fidel Sánchez Hernández laying the first stone.

The stadium, with a capacity of 53,400 is the largest football venue in El Salvador and Central America.

It was announced on 16 November 2007 that Estadio Cuscatlán would become the first football stadium in Central America and Caribbean to have a large LED screen where the supporters can view the action.

Authorities were looking at pressing charges against those responsible for the event and the Salvadoran Soccer Federation suspended all the following day's matches in the country.