He was the son of Isidro de la Rama, a large landowner of sugar cane plantations, who served as one of the vice mayors of Iloilo in 1890, which was granted city rights on January 31, 1890, by the then Minister of Colonies of Spain, Manuel Becerra.
He was temporarily vice president of the veterans' organization Los Veteranos de la Revolución and held the rank of Major General and Commander of the 6th Division of the Philippine Islands National Volunteers.
In 1904, de la Rama ran for governor of the province of Negros Occidental, but was defeated by Antonio Ledesma Jayme.
In fact, the sugar cane plantation owners of Negros and Central Luzon, led by de la Rama and Jorge Araneta, managed to reach an agreement with the then US Governor General James Francis Smith for a reduction in import duties in 1909 and finally in 1913 during the tenure of Taft as US president unrestricted access to the US market.
During the 5th Philippine Legislature from 1919 to 1922, he was granted permission on February 22, 1921, by Laws 2983 and 3035 for a period of 50 years to construct electricity and power plants and the associated infrastructure in what is now Iloilo City to install, expand and operate municipalities of Jaro, La Paz and Arevalo.
Rather, the tenure of eight senators Alauya Alonto, Pedro Hernaez, Domingo Imperial, Vicente Madrigal, Vicente Rama, Eulogio A. Rodriguez Sr., Proceso Sebastián and Emiliano Tria Tirona were extended by drawing lots until November 1947, while the remaining 16 senators were elected in the elections of April 23, 1946 for six and three-year terms respectively.
[20] Another daughter, Amparo de la Rama, was the first wife of the politician Fausto Felix S. Gonzalez, who was a member of the Commonwealth National Assembly between 1938 and 1941 and represented the province of Pampanga's 2nd district.