She began performing in Lisbon at a very young age when her father was engaged by the Teatro de São Carlos.

There, she appeared in the oratorio La morte di Saule by Gaetano Andreozzi [it] (1804) and the operas Nardone e Nannetta by Francesco Gardi [it] (1806) and Ifigenia in Aulide by Luigi Gianella [fr] (1809).

Domenico commissioned Rossini to compose the opera Demetrio e Polibio , for which Vincenza had written the libretto.

She appeared as Desdemona in the theatre's first performance of Rossini's Otello and sang in the world premieres of Carafa's Il paria and Mercadante's Erode and Caritea.

Gritti had been the administrator of La Fenice from 1818 to 1825 and in the ensuing years remained an influential figure in the artistic life of Venice.