Estevan-Big Muddy is a provincial electoral district for the Legislative Assembly of Saskatchewan, Canada.

Known as Saskatchewan's "Energy City", the area has rich deposits of oil, natural gas, and lignite coal.

Provincial Highways 39 and 47 connect Estevan with the American state of North Dakota.

Smaller centres in the riding include the towns of Bienfait, Midale and Radville; and the villages of North Portal, Goodwater, Macoun, Oungre, Halbrite, Torquay and Lake Alma.

For the 2024 general election, the riding gained most of the Big Muddy Badlands area from Weyburn-Big Muddy, and therefore was renamed from Estevan to Estevan-Big Muddy.