Estherton is an unincorporated area and neighborhood in Susquehanna Township, Dauphin County, Pennsylvania, United States, and a part of the Harrisburg-Carlisle area.

Interstate 81 runs through the community to the George N. Wade Memorial Bridge.

Estherton was founded as Coxestown, or Coxtown,[1] in 1756 by Dr. John Cox Jr. after his wife, Esther.

[5] This continued furthermore as the town was a port of call as goods were transported down the river.

[6] Before 1828 the "Coxestown Inn" was formed and was a popular visit for those passing by with the river trade, and would develop a notorious reputation as a rowdy roadhouse that continued through the era of automobile parties; it was later raided by Prohibition Agents before finally burning down in 1926.