[1][2][3][4] During the Second World War, with the rank of lieutenant colonel, he was chief of staff of the 13th Infantry Division Re, fighting in Croatia and later transferred to Rome.

Following the Armistice of Cassibile and the German occupation of Italy, he joined the Clandestine Military Front until the liberation of Rome, after which he rejoined the Italian Co-belligerent Army where he reorganized and commanded the 21st Infantry Regiment of the "Cremona" Combat Group.

[5][6][7][8] In 1946 Musco, having been promoted to colonel, was entrusted with the reorganization of the intelligence services of the newly established Italian Republic.

[9][10][11][12] After promotion to brigadier general, Musco led the Italian military secret service, the SIFAR, from 1952 to December 1955, when he was replaced by Giovanni De Lorenzo on the recommendation of the President of the Republic Giovanni Gronchi, and despite the contrary opinion of Musco himself.

In 1963 he retired from the Army and was awarded the honor of Knight of the Grand Cross of the Order of Merit of the Italian Republic by President Antonio Segni.