Euan Angus Ashley is a Scottish physician, scientist, author, and founder based at Stanford University in California where he is the Arthur L. Bloomfield Chair of the Department of Medicine.

In 2014, they reported in the Journal of the American Medical Association a study of genome sequencing in primary care, demonstrating early detection of pathogenic variations in the breast and ovarian cancer gene BRCA2, and delivering tools for cardiometabolic polygenic risk scoring, and pharmacogenomics.

Developing a pipeline for clinical diagnosis based on aligning, variant calling and filtering Pacific Biosciences SMRT sequencing data, the team identified a previously unrecognized 2 kilobase deletion in PRKAR1A, the gene responsible for Carney complex.

[17] Published in the New England Journal of Medicine and Nature Biotechnology, the team showed that a genetic diagnosis from whole genome sequencing was possible in as little as 7 hours and 18 minutes.

In April 2023, he was awarded the Guggenheim Fellowship,[21][22] a prestigious honor recognizing mid-career scholars, artists, and scientists who have demonstrated a previous capacity for outstanding work and continue to show exceptional promise.

According to the publisher's notes, the title “...explains the basic physiology and pathophysiologic mechanisms of cardiovascular disease in a straightforward and diagrammatic manner, gives guidelines as to when referral is appropriate, and, uniquely, explains what the specialist is likely to do.” Ashley released the non-fiction title The Genome Odyssey: Medical Mysteries and the Incredible Quest to Solve Them [25][26] on February 23, 2021, with Celadon Books, a division of Macmillan Publishers.

The book features stories of patients and families from Ashley's medical practice and walks through the science underlying those diseases, shining a spotlight on some of the scientists.

New York Times best-selling author Abraham Verghese remarked that The Genome Odyssey was “destined to be a landmark narrative in the canon of modern science.” The Pulitzer Prize winning author Siddartha Muhkerjee wrote that “Dr Ashley, one of the pioneers of gene sequencing technologies, writes with authority, elegance and simplicity.” The Wall Street Journal described The Genome Odyssey as an “impassioned, firsthand account of the effort to bring genomic data into clinical practice.” Ashley has appeared on National Public Radio in the United States as well as the BBC radio, Japanese and Indian national television, and NBC Evening News.

In 2012, Ashley co-founded Personalis,[29] a genome-scale diagnostics company with Stanford colleagues Russ Altman, Atul Butte, Mike Snyder and businessman John West.

Deepcell develops imaging and microfluidics platforms that use artificial intelligence to identify and isolate viable cells based on morphological distinctions.

Ashley is co-founder and chairman of the board at Silicon Valley Exercise Analytics (Svexa),[31] a sports intelligence company that combines physical, subjective and biological data to offer optimized training, performance and recovery recommendations for athletes and teams.

They released two albums (Cookin' with the HDQ and A Train in the Distance) appeared multiple times on BBC Radio and contributed an arrangement of Charlie Mingus’ Haitian Fight Song to the David Byrne-produced soundtrack for the movie Young Adam featuring Ewan McGregor, Tilda Swinton, and Emily Mortimer.

Ashley also performed in duo and quartet format at the Glasgow International Jazz Festival with Malcolm Finlay, Stuart Brown and others as part of the group Universal.

While at Oxford University, Ashley directed the Oxford University Jazz Orchestra a period of tenure that included band tours to the Glasgow International Jazz Festival, honors at the BBC big band competition, and the release of the live album Know Where you Are with bebop legend Peter King.