Reading the letters of Paul the Apostle led Eucherius to seek the monastic life in 714, when he retired to the Abbey of Jumièges in the Diocese of Rouen.

The reputation of his virtue must have been very great, for a deputation was sent to Charles Martel, then mayor of the palace, who practically governed the Frankish Kingdom, to beg that Eucherius might be elected to the vacant see.

Having opposed the elevation of Charles Martel and the latter's confiscation of church property to fund his war efforts against the Moorish invasions from Al-Andalus, Eucherius found himself out of favor with the new Carolingian dynasty.

When Charles Martel returned from his victory at the Battle of Tours, he stopped in Orléans and exiled Eucherius to Cologne.

Hincmar of Reims reported to a Council of Quierzy in 858, a vision that Bishop Eucherius of Orléans had seen during the reign of King Pepin III over a century before.