Eufaula National Wildlife Refuge is an 11,184 acre (45.26 km2) National Wildlife Refuge located in Barbour and Russell counties in Alabama and Stewart and Quitman counties in Georgia.

Eufaula NWR was established in 1964 in cooperation with the United States Army Corps of Engineers which manages the Walter F. George Lock and Dam and the majority of Walter F. George Lake.

The Eufaula NWR protects endangered and threatened species such as the wood stork.

Other wildlife species include raccoon, white-tailed deer, quail, beaver, red and gray fox species, dove, bobcat, hawk, armadillo, owl, rabbit, squirrel, river otter, turkey, and coyote, not to mention other reptiles (alligators and copperheads), amphibians, insects and various fishes.

Lake Eufaula offers several activities including boating and fishing.