Eugène-Louis Lequesne (French pronunciation: [øʒɛn lwi ləkɛn]; or Le Quesne; 15 February 1815 – 3 June 1887) was a French sculptor.
In 1841, he entered the École nationale des beaux-arts, in James Pradier's workshop.
In 1843, he won the second Prix de Rome, and in 1844 the first prize, with a plaster bas-relief entitled Pyrrhus tuant Priam (Pyrrhus killing Priam).
He lived at the Académie de France à Rome from 1844 to 1849, alongside Jean-Louis Charles Garnier.
In 1855, he was awarded the Great Prize for sculpture at the Exposition Universelle, and received the Légion d'honneur.