[5] They started their project of the 20th anniversary debut with released digital single "Love[Story]", a remake of their 1999 single "Love", through SM Entertainment's digital project SM Station on November 28[6] and its music video released on December 29.

[7] In early December 2016, they aired their ten episode reality show Remember, I'm Your S.E.S., which broadcast through mobile app Oksusu.

To accompany their 20th anniversary debut, they held a concert, Remember, the Day, on December 30 and 31 at Sejong University's Daeyang Hall in Seoul.

Her first album sold nearly 65,000 records and had one hit ballad, "The Best" which included bonus tracks, "Jesus loves me", in which she handwritten the lyrics to this special mashup.

After the success of her previous program Eugene's Makeup Diary, cable style network O'live again chose her as the host of new show Get It Beauty which began airing in July 2010.

[22] In 2012 she became the host of season 3 of MBC's revamped flagship amateur singing competition show The Great Birth.

[23][24] Her next leading role was in the 2013 weekend family drama A Hundred Year Legacy, which reached ratings of over 30 percent.

[31] On August 12, 2022, Eugene held a fan sign event in front of the Lotte World Mall Jamsil store.

[32] On May 11, 2011, Eugene announced that she would be married to Ki Tae-young, her leading man in the 2009 TV series Creating Destiny.

[39] After the sinking of the MV Sewol, fans of Eugene began to doubt her belief in the Evangelical Baptist Church of Korea.