She modelled for Augustus John and Jacob Epstein and came to exemplify the sexual freedom of the bohemian lifestyle of the early twentieth century.

[2] Her working-class accent, however, was not to everyone's taste, and Viva King, another bohemian, said of one of Jacob Epstein's busts of Euphemia, "I fancy I can hear, through the open mouth, her ugly voice".

Henry enrolled at the Chelsea School of Art that had recently been established by Augustus John and William Orpen and they attended the Friday Club run by Vanessa Stephen.

On one occasion, according to Euphemia, her penchant for dressing like a man had unfortunate consequences, she and John were arrested as homosexuals and she was required to undress in custody in order to prove she was a woman.

[3][15] She also claimed that she had a revolver and was prepared to shoot herself and her husband, and that she had caused the death of John's first wife Ida who had died in childbirth.

[3] Battles with Henry forced Euphemia in the direction of Duncan Grant,[2] whose relationships were usually homosexual, but he was repulsed by the complicated love life of the group, particularly John's encouragement of Dorelia's relationship with Henry, writing to Lytton Strachey, "That Lamb family sickens me", and referring to Euphemia as "the white haired whore".

[15] Around 1910, Epstein completed for Lady Ottoline Morrell a garden figure of 53 inches (1,300 mm) for which Euphemia was the model.

[4][20] Crowley gave Euphemia the name "Dorothy" in his Confessions[3] and described her as "incomparably beautiful ... capable of stimulating the greatest extravagances of passion".

Visitors included John and Dorelia, Derwent Lees, Ian Strang, and Euphemia, who Innes painted against the background of Arenig Fawr.