EUYO is an associated member of the European Federation of National Youth Orchestras[4] and is supported by the Creative Europe programme.

In 2014, EUYO launched the Towards 2020 (T2020) project, aiming to change the face of classical music in Europe by training young musicians to engage with 21st century audiences.

[11] Since the expiration of the Brexit transition period on 31 December 2020, members from the United Kingdom are no longer eligible to apply.

[16] EUYO has also worked with guest conductors including Daniel Barenboim, Leonard Bernstein, Herbert Blomstedt, James Conlon, Colin Davis, Antal Doráti, Carlo Maria Giulini, Herbert von Karajan, Rafael Kubelík, Erich Leinsdorf, Lorin Maazel, Zubin Mehta, Gianandrea Noseda, Kurt Sanderling, Gennady Rozhdestvensky, Mstislav Rostropovich and Georg Solti.

[citation needed] Soloists that have appeared with EUYO include pianists Martha Argerich, Vladimir Ashkenazy, Emanuel Ax, Evgeny Kissin, Radu Lupu, Julian Lloyd Webber, Murray Perahia, Maria João Pires, Mikhail Pletnev, Maurizio Pollini, violinists Itzhak Perlman, Renaud Capuçon, Kyung Wha Chung, Janine Jansen, Leonidas Kavakos, Daniel Hope, Nigel Kennedy, Yehudi Menuhin, Midori, Viktoria Mullova, Anne-Sophie Mutter, Arabella Steinbacher, Pinchas Zukerman, and singers Diana Damrau, Plácido Domingo, Dietrich Fischer-Dieskau, Angela Gheorghiu, Matthias Goerne, Susan Graham, Christa Ludwig, and Jessye Norman.

[18] The Guardian described the EUYO as having "gripping, exhilaratingly good orchestral playing, surging with energy, laser-sharp focus and collective daring", with "a technical prowess that is downright terrifying".

[20] The Times has called EUYO "the cream of Europe's talent", and that "post-Brexit, this closed door for the UK will be a valuable cultural opportunity lost".