Port of Holyhead (53°18′34″N 4°37′44″W / 53.3094°N 4.6289°W / 53.3094; -4.6289) Port of Immingham (53°37′38″N 0°11′27″W / 53.62718°N 0.19097°W / 53.62718; -0.19097) Amsterdam (52°22′N 4°54′E / 52.367°N 4.900°E / 52.367; 4.900) Bad Nieuweschans (53°10′50″N 7°12′26″E / 53.18056°N 7.20722°E / 53.18056; 7.20722) Bunde (53°11′N 7°16′E / 53.183°N 7.267°E / 53.183; 7.267) Sassnitz (54°30′59″N 13°38′28″E / 54.51639°N 13.64111°E / 54.51639; 13.64111) There are currently plans to reroute the E22 between Lübeck and Westerstede, to go north of Hamburg and Bremen over the A20, when this new motorway is built after 2020.

[citation needed] Trelleborg (55°22′N 13°10′E / 55.367°N 13.167°E / 55.367; 13.167) Norrköping (58°36′N 16°12′E / 58.600°N 16.200°E / 58.600; 16.200) In Sweden, E-Roads do not have national numbers.

There is currently no ferry across the Baltic Sea between Norrköping and Ventspils.

Ventspils (57°23′26″N 21°34′24″E / 57.39056°N 21.57333°E / 57.39056; 21.57333) Zilupe (56°23′N 28°07′E / 56.383°N 28.117°E / 56.383; 28.117) Burachki (56°21′22″N 28°11′38″E / 56.356°N 28.19383°E / 56.356; 28.19383) Ishim (56°07′N 69°30′E / 56.117°N 69.500°E / 56.117; 69.500) Between Kazan and Igra, the road takes a detour over Yelabuga, because the shortest route between Kazan and Igra uses a ferry over the Vyatka River (56°35′31″N 50°42′32″E / 56.592°N 50.709°E / 56.592; 50.709), and the road is a bad gravel road around that area.

Google Maps shows the E22 to use the ferry, but that is inaccurate; the UN convention lists Yelabuga along a paved road without any ferry.