Tourists are also attracted to Euskirchen due to the proximity of two large cities, Cologne and Bonn, to the northeast, and the hills of the Eifel region to the south.

Until a few decades ago, a further important branch of industry was cloth manufacturing, but this was unable to survive due to competition from large international corporations.

The town's central location and good road and rail links to the international transport network are important factors in this context.

The two largest industrial and commercial sites in Euskirchen, accounting for a total of 21,000 jobs between them, are: At IPAS, in the districts Wüschheim/Großbüllesheim, the consumer goods corporation Procter & Gamble has a production plant as well as a warehouse from which it conducts its logistics operations all over the world.

[10] With a total area of 205 hectares, which is equivalent to about 300 football fields, the "PrimeSite Rhine Region" is the first unbuilt and available industrial and commercial site of this size in North Rhine-Westphalia to date.