Formerly known as Eustace Hall, Eustace-Cole Hall located on Laboratory Row is the only building on Michigan State University's main campus in East Lansing, Michigan that is on the National Register of Historic Places.

Designed in a mix of "Queen Anne massing, Richardsonian Romanesque features, and Shingle Style",[3] it was built in 1888 as the Horticultural Laboratory Building.

It then became the University College Building until 1961 when it was renamed for Harry J. Eustace who chaired the Horticulture Department from 1908 to 1918.

[5][6] [7] The third-oldest extant building on the MSU campus, it was listed on the Michigan Register of Historic Places on March 3, 1971 as the Horticultural Laboratory Building and was listed on the National Register on September 3, 1971 as Eustace Hall.

[1][5] In 1999, Eustace Hall underwent a $3 million renovation funded in part by a major donation from MSU alumni Jeffrey N. Cole (BS, 1970)[8] and Kathryn C. Cole (MBA, 1990) of Birmingham, Michigan and was renamed Eustace-Cole Hall in their honor.