22 August] 1879 in Adjigiol village[3][4] near Ochakiv, in the Kherson Governorate of the Russian Empire, but some records report that she was born in Ochakiv, Kherson Governorate in a family of a German colonist, mechanic, and landowner Gotlieb Meisch, and Bessarabian noblewoman Maria Krusser.

For three years, Yevgenia attended Voznesensk Female Gymnasium, after which, due to a health condition, she worked for her stepfather as a secretary.

Her older brother Oleksiy acquainted her with his friend Peter Bosch, who was an owner of a local small wagon shop.

According to another source, Yevgenia Bosch was born in Ukraine to Gottlieb Meisch, an ethnic German immigrant from Luxembourg, and his Moldavian wife.

[6] At age 17, her parents attempted to arrange a marriage to an older man, but she rebelled and married a bourgeois businessman named Peter Bosch.

The police search was unsuccessful, but Bosch left her husband and fled to Kyiv, where she joined the revolutionary underground.

In Kyiv, she established contact with the local Bolshevik faction, and together with her younger sister Elena Rozmirovich (future wife of Nikolai Krylenko, chekist), conducted underground revolutionary activities.

Alongside Pyatakov, Bosch managed to escape from Kachuga volost (Upper-Lena uyezd, Irkutsk Governorate), first to Vladivostok, and then, with a short stint in Japan, to the United States.

The decrees of the Petrograd Council of People's Commissars extended to Ukraine and an official alliance with the Russian Red Army was declared.

She resigned her government post in protest and organised worker battalions to resist the advance of the German army through Ukraine.

She became ill with tuberculosis and heart disease, however, and after several months of recuperation, she left Ukraine for Russia, where she filled political and military administrative posts for the next few years as the civil war continued.

[5] In August 1918, she was the chairwoman of the Penza Governorate Party Committee during the controversy that led to the issue of the so-called Lenin's Hanging Order.

In 1919, she was a member of the committee for the defence of Lithuania and Belarus, and then served as a political commissar for the war against General Denikin.

In 1924, she succumbed to despair after hearing that Trotsky had been forced to resign as leader of the Red Army, as well as in pain from her heart condition and tuberculosis; she died by suicide from a self-inflicted gunshot in January 1925.

[5][12] Her suicide was met with an immediate, deliberate effort by the Soviet government to suppress official acknowledgement of her status as a major Bolshevik leader.

There was no national funeral, only a local one; no urn in the Kremlin wall, only a place befitting her rank in the plot reserved for communists in the Novo-Devichy cemetery.