Born in Iron Mountain, Michigan, DeConcini and his family soon moved to Wisconsin.

He began studies at the University of Wisconsin in 1920, but his father's death in an automobile accident in February 1921 led to the family's relocation to Arizona, where DeConcini's father had purchased some properties.

[2] Around 1928, DeConcini developed the Government Heights subdivision just south of the VA Hospital (now known as the Southern Arizona VA Health Care System) in Tucson, Arizona.

Prominent attorney Daniel Cracchiolo served as law clerk to Arizona Supreme Court Justice Evo DeConcini in 1952.

[5] In 2000, the newly built Federal Courthouse in Tucson, AZ was named in honor of Evo A.