They were joined by the crew of Soyuz MS-18, which is made up of Russian cosmonauts Oleg Novitsky and Pyotr Dubrov, as well as NASA astronaut Mark Vande Hei.

On 5 October 2021, Soyuz MS-19 launched, carrying Russian cosmonaut Anton Shkaplerov, film director Klim Shipenko and actress Yulia Peresild.

The iROSA also encountered technical problems with deployment, resulting in the spacewalk being cut short early, having lasted 7 hours and 15 minutes.

[13][1] The 20 June spacewalk, begun at 11:42 UTC and lasting 6 hours and 28 minutes, saw the first iROSA's successful deployment and connection to the station's power system.

[16][1] One more spacewalk, comprising a plasma measuring instrument replacement and a bracket installation on the P4 Truss for the next iROSA pair, was planned for 24 August, to be conducted by Akihiko Hoshide and Mark Vande Hei.