In Italy he is mostly known for his long-lasting appearances in TV shows like Drive In and Striscia la notizia, while abroad he is noted for his movies and his collaboration with Mel Brooks.

Born in Cossato, a small town near Biella,[1] Greggio began his TV career at age 18 in Telebiella, the first local private owned station in Italy thanks to the help of founder Peppo Sacchi.

D'Angelo convinced Greggio to move to the newborn Fininvest (later Mediaset), a local TV channel founded in Milan by Silvio Berlusconi.

Drive In was a very innovative show, and had great success giving national fame to almost all the actors involved, like Enrico Beruschi, Giorgio Faletti, Teo Teocoli, Francesco Salvi, Carlo Pistarino, Enzo Braschi and many others, including of course Greggio and D'Angelo.

[citation needed] Brooks named one of Dom DeLuise's killers in his Robin Hood: Men in Tights, "Dirty Ezio", and had Greggio in the cast of Dracula: Dead and Loving It.

[citation needed] Since 2000, Greggio acted in a great number of TV productions tho he would return to movies once more in 2011 with Box Office 3D: The Filmest of Films.