Ezra Thompson (1850–1923) was the 12th and 14th mayor of Salt Lake City, Utah, US, who was elected three times and served two non-consecutive terms.

Thompson was born on July 17, 1850, in Salt Lake City in the Provisional State of Deseret, just months before Utah Territory was created.

He made his fortune in a Park City mining venture with future United States Senator from Utah Thomas Kearns.

[1] In 1899, he was elected mayor of Salt Lake City on the Republican Party ticket.

In January 1903, Thompson was a signatory of an official protest to the United States Senate of the Utah Legislature's election of Mormon Apostle Reed Smoot as a United States senator for Utah.