The team was first created by professor Istvan Kiss[1] as a women's squad associated to his futsal club City'US Târgu Mureș.

In 2008 a new entity that was to receive generous funding from the municipality of Târgu Mureş was formed, and the women's team switched to this club, participating in competitions under the name of FC Municipal Târgu Mureș, garnering success and immediately winning both the Liga I[2] and the Romanian Cup.

As such, they participated in the 2010–11 UEFA Women's Champions League qualifying round, where they won one of three matches, but failed to move on.

Financial difficulties became prevalent during the 2016–17 season, and especially during the 2017–18 one, when the team withdrew halfway through the championship, due to the municipality refusing to fund the club and others associated with it, citing irregularities that have been brewing in this period.

Meanwhile, most of the women football players signed with local side Ladies Târgu Mureș until the summer, when they were recalled in order to restore the refounded team to its previous glory.