FC Buffalo joined the NPSL as an expansion franchise in 2009 and took part in its first competitive season in 2010 with games held between the Demske Complex at Canisius University and Robert E. Rich All High Stadium.

The team is owned by a group of five Buffalonians: Joshua Batten, Scott Frauenhofer, Donny Kutzbach, Nick Mendola, and Ray Siminski.

The club had a contest for fans to submit a nickname and after much debate and thousands of votes cast, "Blitzers" was chosen.

The vote was aided by Buffalo native and CNN broadcaster Wolf Blitzer airing an interview with owners Nick Mendola and Scott Frauenhofer discussing the contest.

ESPN correspondent Vincent Thomas commented: "Although the 'Blitzers' nickname has ended up being a pretty deft marketing move, it's more legit than a ploy.

Krzyzanowicz helmed a Medaille College program that has made the NCAA tournament five times and reached the Sweet Sixteen in 2010.

[2] The match was filmed and later made into a BBC documentary called Mr Rich and The Terriers[3] The team's mascot Wolf Blitzer was unveiled at the Winter Wolves fund raiser.

The club elevated Butcher into an administrative position in 2021, hiring Ryan "Ozzy" Osborne as first team men's coach.

On May 9, 2022, the team announced that they would play their home games for the 2022 season at Dobson Field on the campus of D'Youville University while All-High Stadium is renovated.

The badge features a crest with a soccer ball inside a circle of electric flashes under the team name and founding year.

Més Que, Buffalo's premier downtown soccer bar, and Batavia Downs Gaming & Casino are the two other shirt sponsors.