The club, which transformed itself into the Associazione Sportiva Materana in the 1936-37 championship, remained the city's highest expression of football until the Second World War.

During the war, Matera was the only non-Apulian team to participate in the 1944 CONI Cup, a competition played in Puglia liberated by the Allied forces, while in the 1944-1945 Apulian mixed tournament, they withdrew at the end of the first round.

He was therefore admitted to the new Lucanian Promotion championship, winning it in 1953 and returning to the interregional category, which in the meantime changed its name to IV Series, where he participated for five consecutive seasons.

Matera for 22 years, Franco Salerno, who later also became Senator of the Republic, who will bring the blue and white club in the seventies to its highest levels ever.

Later he will also win the Jacinto Trophy, a precursor tournament to the current Amateur Scudetto (established since 1992) played between the six winners of the promotion play-offs; beating Aosta 1–0 in the final in Bovalino, Matera then became Interregional Italian Champions.

Polisportiva Matera, in protest against the relegation and economic difficulties, played the 1997-98 National Amateur Championship with the junior team, finishing second to last in group H with only 6 points and ahead of only Lagonegro.

In 1998, the Materasassi Sports Association was born from the merger between Atletico Matera and Scanzano, chaired by the lawyer Vitantonio Ripoli, who acquired the right to participate in the regional Eccellenza tournament.

In 1999-00 Materasassi, which in the previous season played at a regional level had come in third place by winning the Italian Amateur Basilicata Cup, won the Eccellenza championship and allowed Matera football to return to an interregional category after two years.

In the 2004–2005 season, due to the usual lack of investors, it was the fans who guaranteed food and accommodation to the players thanks to real spontaneous collections of money which continued until the entry into the club of the two new Barbano members and Padula.

In 2022–23, after an extremely difficult start under the guidance of coach Finamore, who decided to resign in the month of October, with the appoint of mister Ciullo the biancazzurri managed to climb back up the table with a series of consecutive useful results, up to hope for a place in the playoffs.

At the time of the founding of the first city football team, from which Matera Calcio derives, the maroon was initially chosen as the social color.

Its construction was completed in 1933 and it was initially called Campo Sportivo Luigi Razza; after the war the name was changed to Stadio XXI Settembre to commemorate September 21, 1943, the date of the Matera massacre.

Precisely in 1979, on the occasion of that promotion, the stadium was renovated, with the construction of the two curves and the steps, the latter replacing the old one that was made of Innocenti tubes and of much smaller dimensions, while the central grandstand dates back to the early fifties and the side stands to 1968; the total capacity of the stadium was thus increased to about 15,000 seats, progressively reduced over the following years for reasons of security and public order.