Fútbol Club Santiago de Cuba is a Cuban professional football club based in the city of Santiago de Cuba, which currently plays in the Campeonato Nacional.

It was promoted to Campeonato Nacional for the 2015 season.

[1] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

This article about a Cuban football club is a stub.