[1] The College of Medicine received full accreditation from the Liaison Committee on Medical Education in February 2013.

[3] In April 2023, medical school dean Dr. Juan C. Cendan announced that the Wertheim College of Medicine is partnering with Baptist Health South Florida, the largest healthcare organization in the region, to form an academic healthcare system that would serve Miami-Dade and Broward counties.

In its inaugural 2009 class, the FIU College of Medicine received 3,247 applicants; 126 were admitted, and 43 were enrolled.

FIU Herbert Wertheim College of Medicine has announced that it is finalizing a comprehensive alliance[8] with Baptist Health South Florida that will expand undergraduate and graduate medical education programs, develop clinical and teaching facilities, grow faculty-physician practices, and deepen capabilities around research.

Currently, the college works in affiliation with a variety of clinical community partners,[9] including Baptist Health South Florida, Broward Health, Citrus Health Network, Cleveland Clinic Foundation Florida, Jackson Health System, Memorial Health Care System (Hollywood), Mercy Hospital (Miami), Mount Sinai Medical Center (Miami), Miami VA Healthcare System, North Shore Medical Center, Westchester General Hospital, Palmetto General Hospital, Kendall Regional Medical Center, South Florida Evaluation and Treatment Center.