The class is commonly known by the nickname Signorine (Italian for 'young ladies', also shared with the similar Class 640 locomotives),[1] or Signorina in the singular, because of their perceived grace and beauty compared to other locomotives.

A number of locomotives in the class were retained in mothballed working condition as part of Italian Railways' policy of keeping steam locomotives in reserve, well into the era of internal combustion and electric motive power.

Locomotive 625 116 featured in the 2013 Italian cinema film The Magistrate by Giulio Base.

Twenty-five Class 625 locomotives survived into preservation; amongst them 625.100, 625.116 (private museum owner), 625.142 and 625.177 are currently operational and available for heritage trains.

[3][4] Of particular note is 625.308, the only remaining FS locomotive with internal Caprotti valve gear, currently being restored at Pistoia.