[15] The School of chemistry also offers six 4.5-year undergraduate degrees:[16] Most of the School's buildings are located in the main campus of UNAM, Ciudad Universitaria (University City, south Mexico City), while two more external campuses are also part of the School, the External Complex of Tacuba (Conjunto Externo de Tacuba), in Tacuba, west Mexico City, and the Sisal Foreign Station (Estación Foránea de Sisal), in Sisal, Mérida, Yucatan, south-east Mexico.

However, the harsh national and international context, derived from the Mexican Revolution movement and World War I affected the availability of highly skilled personnel.

[19][20][21] Therefore, in January 1913, Juan Salvador Agraz presented an initiative to the mexican president Francisco I. Madero to create the School of Chemistry.

On September 23, 1916, the Mexican president Venustiano Carranza promulgated by government-decree the foundation of the National School of Industrial Chemistry (Escuela Nacional de Química Industrial, and later Escuela Nacional de Ciencias Químicas or National School of Chemical Sciences) in the town of Tacuba (north-west to Mexico City).

In a similar manner, the school installed an ether production plant and created new buildings for fermentative, sugar and starch processing, tannery chemicals and pharmaceutical industries.