Fakhr al-Din was briefly imprisoned by the Mamluk authorities in 1505 in relation to his alliance with the Bedouin Bani al-Hansh clan against the Mamluk-appointed, Druze governor of Beirut.
The Ma'n family, to which Fakhr al-Din belonged, established itself in the Chouf (Shuf) area in southern Mount Lebanon, where they founded their headquarters at Baaqlin, in 1120.
Uthman who is supposed to have submitted to the Ottoman Sultan Selim the Grim in 1517 at Damascus and to have been confirmed in the chieftainship of the Jebel Druze [Mount Lebanon], cannot have been reigning at that time".
[8] A 1493 inscription on a mosque in Deir al-Qamar credits "al-Maqarr al-Fakhri [the Fakhrid Seat] Emir Fakhr al-Din Uthman" as its builder and further notes that he was the "son of al-Hajj Yunis ibn Ma'n".
[8][9] According to the historian William Harris, in the 1490s Fakhr al-Din entered into an alliance with the Bani al-Hansh, a Sunni Muslim clan that controlled most of the Beqaa Valley at the time.
The Bani al-Hansh were at war with the Buhturids (descendants of Jumayhur Buhtur) led by Jamal al-Din Hajji, the Mamluk-appointed governor of Beirut between the 1490s and 1512.
[10] Fakhr al-Din was succeeded by his son Yunis, who according to Ibn Sibat died "a young man of reverence, power, and dignity" in 1511-12.