Family Skeleton is an American old-time radio serial drama, "the story of a girl with a dark past and highly uncertain future.

She became the "family skeleton" because she arrived at her home pregnant "with her marriage license obliterated by bloodstains" and could not prove her marital status.

Others in the cast included Parley Baer, Michael Ann Barrett, Tony Barrett, Mary Jane Croft, Dix Davis, John Dehner, Sam Edwards, Eddie Firestone, Frank Gerstle, Robert Griffin, Bill Idelson, Byron Kane, Lou Krugman, Earl Lee, Forrest Lewis, James McCallion, Kate McKenna, Howard McNear, Marvin Miller, George Neise, Jeanette Nolan, Jay Novello, Ruth Perrott, Ken Peters, George Pirrone, Alice Reinheart, Janet Scott, Marilyn Steiner, Russell Thorson, Les Tremayne, David Vail, and Ben Wright.

[4] Carlton E. Morse, who created Family Skeleton specifically for McCambridge, produced the program and wrote its scripts.

Ron Lackmann, in his biography of McCambridge, described the show as being "loosely based on Morse's immensely successful One Man's Family program.