On 28 January 2024, a Shahed 136 drone strike carried out by the Islamic Resistance in Iraq targeted Tower 22, a US base in Jordan, resulting in the deaths of three US troops and causing injuries to 47 others.

[11][12] Around midnight between 2 and 3 February local time (UTC+3), the United States Air Force carried out airstrikes targeting Iran-affiliated militia groups in Iraq and Syria.

[6] At 9:30 p.m. local time, the United States conducted a drone strike on a vehicle in Baghdad, resulting in the death of three Kata'ib Hezbollah militants, among them senior commander Abu Baqir al-Saadi.

[20] Satellite imagery by Planet Labs revealed the extensive destruction of a facility utilized by the Liwa Fatemiyoun militia in the town of Ayyash, near Deir Ez-Zor in Syria.

[4] In Iraq, a funeral was held in Baghdad for 17 militiamen killed by the airstrikes on 4 February, with crowds chanting "America is the greatest devil" and holding pictures of the victims besides the ambulances transporting their remains.

[21] President Joe Biden wrote in a statement that their response to the drone attack in Jordan had begun and would "continue at times and places of our choosing.

"[22] Secretary of Defense Lloyd Austin referred to the strikes as "the start of our response" and that Biden had "directed additional actions to hold the IRGC and affiliated militias accountable for their attacks on U.S. and Coalition Forces.

[24] The Ministry of Foreign Affairs condemned the attacks, calling it a "strategic error by the US government which will have no result but to intensify ... instability in the region".

[28] The spokesperson for Harakat Hezbollah al-Nujaba, Hussein al-Mosawi, said that the US "must understand that every action elicits a reaction" and also saying that "We do not wish to escalate or widen regional tensions.