[3] George Jung, the basis for the 2001 film Blow, served time at FCI Otisville, but was later transferred to the Federal Correctional Institution in Fort Dix, New Jersey, before being released in 2017.

In the Spike Lee film 25th Hour, the protagonist Montgomery "Monty" Brogan spends his final day commiserating with friends and family before reporting to Otisville for a seven-year sentence.

In 2019, Mike "The Situation" Sorrentino, who is famous from the MTV show Jersey Shore, was sentenced to eight months for tax fraud.

In Season 3 Episode 4 of Succession, Tom Wambsgans mentions Otisville as "the Jewish jail" while looking through a list of prisons where he will potentially be incarcerated.

[4] Aleph Institute's prison outreach director, Rabbi Menachem Katz, stated that the BOP is "unofficially designated it to meet the needs of Orthodox Jews" due to the proximity to the Jewish population of New York City.